INTERNATIONAL 8th USBİLİM HEALTH, ENGINEERING AND APPLIED SCIENCES CONGRESS
QUANTITATIVE DETERMINATION OF PHYTOCHEMICAL COMPONENTS OF ETHANOL EXTRACTS OF Muscari comosum (L.) Mill. SPECIES BY LC-MS/MS
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Muscari comosum (L.) Mill., commonly known as Purplebas, grows naturally in the Mediterranean region and its bulbs are used as a vegetable. Traditionally, they have also been used to treat various diseases and ailments, which has inspired the study of the pharmacological activities of the different parts of M. comosum. M. comosum is a perennial bulbous flowering plant belonging to the Asparagaceae family. The bulbs of the plant are pink to reddish, spherical to oval. M. comosum is currently referred to in some sources as Leopoldia comosa. The genus name comes from the Ancient Greek for musky odor and in this context draws attention to the pleasant odors of some species of the genus. It is often called tassel hyacinth or tassel grape hyacinth. The Turkish name of the genus, müşkürüm, is also clearly derived from the genus name. The species name comes from the Latin for many-leafed. In Turkey, it is naturally distributed in Istranca, Çatalca-Kocaeli, South Marmara, Aslı Aegean, Inner Western Anatolia, Upper Sakarya, Middle Kızılırmak, Upper Kızılırmak, Upper Euphrates, Upper Murat-Van, Hakkari, Antalya, Adana, Middle Euphrates, Tigris sub-regions. In the Mediterranean region, it is found in rocky grounds such as cornfields and vineyards and in cultivated areas, but it has also grown naturally in other places. M. comosum easily becomes naturalized and can become invasive. It is known in the literature that the bulb of the plant is an appetite stimulant and diuretic. The onion is rich in mucilage and is applied to skin rashes in poultice form. The plant has been used in Anatolia in the treatment of eye disorders and skin diseases. Dioscorides reported that the edible plant native to Africa was beneficial to the stomach and intestines, and was used in cases of dislocations, bruises, hemorrhoids, hernias, dark circles under the eyes, freckles, dog bites, edema and joint pain, and was used as a dandruff remover, sexual desire enhancer, nutrient and digestive aid. It is stated in the literature that M. comosum, when applied alone or with honey, is good for sprains, bruises, splinters, joint pain and gout. In this study, M. comosum species was collected in the flowering period in Mardin province and the ethanol extracts of the species were quantitatively determined by LC-MS/MS for phytochemical components. The phytochemical contents in the seeds, roots, branches, flowers and leaves obtained from the plant were determined. According to our results, phytochemicals such as kaempferol (1.032 mg/g) were detected in the root part of the plant, Quinic acid (0.606 -0.605) in the seed and flower parts and p-Coumaric acid (0.239) in the seed part.