6. INTERNATIONAL CONGRESS ON CONTEMPORARY SCIENTIFIC RESEARCH
EXERCISE METHODS USED IN EXPERIMENTAL ANIMALS
The first steps towards animal ethics were taken towards the middle of the twentieth century. When we look at the historical development, it can be seen that the first important regulation was the UNESCO “Universal Declaration of Animal Rights” dated October 15, 1978. The first important and serious step regarding the ethics of experimental animals in Turkey was started in 2004. The first “Animal Experiments Central Ethics Committee and Local Ethics Committees” were established in July 2007. Exercise and physical activity function as a pathophysiological process that can prevent, reduce, manage and regulate many chronic conditions including metabolic syndrome, epilepsy, obesity and many other diseases. Due to the ethics and technical difficulties of research in humans, exercise models on animals are necessary for the future development of exercise mimics to treat such abnormalities. In addition, due to concerns such as research ethics, duration, time and technical difficulties related to human studies, it is necessary to use different animals to study exercise. Important points to consider when implementing treadmill exercise and swimming exercise studies: In the most appropriate exercise protocol for the subject to be studied (aerobic, anaerobic, voluntary, involuntary, chronic, acute) used in the experimental animal, the first thing to be considered is the exercise run to get the animals used to it and not to get stressed, the time of the exercise and the daily repetition time to prevent the routines of the rats or mice from being disrupted, the age of the experimental animal, the willingness of the experimental animal to participate voluntarily in the exercise, and the type of animal to be used.
