3. BİLSEL INTERNATIONAL TRUVA SCIENTIFIC RESEARCHES AND INNOVATION CONGRESS
EXAMINATION OF THE RELATIONSHIP BETWEEN EXPOSURE DURATION WITH GRIP STRENGTH AND CORTICAL SENSATION IN INDIVIDUALS WITH SUBSTANCE USE DISORDER: PILOT STUDY
Substance use disorder (SUD) can lead to long-term changes in brain regions related to body movement and movement, and problems with gait, posture, sensation, speed and stiffness of movement, apathy, and coordination. In addition, increased excitability of the motor cortex can lead to problems in the pathway from the motor cortex to the hand muscles and abnormal manipulation of new objects. Our study aimed to examine the relationship between the duration of substance exposure with grip strength and cortical sensation in individuals with SUD. Individuals who applied to Ankara Training and Research Hospital, Alcohol, and Substance Dependence Treatment Centre for treatment and who were diagnosed with SUD according to DSMV were invited to participate in the study. Individuals who volunteered to participate in the study, aged 18-45 years, who had been using substances for more than 1 year, and whose Mini Mental Test score was 24 or higher were included. Individuals with any orthopedic, neurological, and systemic disorders that may cause obstacles to the evaluations to be made within the scope of the study were not included in the study. Demographic characteristics of the individuals were recorded. Jamar® hand dynamometer and Jamar® pinchmeter were used to evaluate grip strength. A static two-point discrimination test was used to evaluate cortical sensation. The results were analysed with appropriate statistical methods. A total of 33 individuals, 29 males (87.87%) and 4 females (12.12%) were evaluated in the study. The mean age of the individuals was 27.18±5.91 years and the duration of exposure to the substance was 126.54±76.5 months. A low-moderate and significant positive correlation was found between the duration of exposure and hand grip strength and tip pinch grip strength in the dominant extremity (respectively, rs=0.383, p=0.028; rs=0.392, p=0.024). It was determined that there was no correlation between exposure time and cortical sensation (p>0.05). As a result of our study, it was observed that muscle strength increased with increasing exposure time in individuals with SUD. Accordingly, high grip strenght application of individuals may lead to impairments in fine motor skills and adverse conditions in daily life activities.
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